Interictal epileptic discharge > 1% associated with cognitive impairment in adult patients with epilepsy: A cross-sectional study based on dose-response relationship and discharge characteristics

Aggregator

29 Oct 2026 0 comments

CONCLUSION: A sleep IED index > 1% may represent a candidate electrophysiological marker of domain-specific cognitive vulnerability, whereas a wakefulness threshold and clear regional specificity were not definitively established. These findings support vigilance-state-aware quantification of IED burden while highlighting the need for larger longitudinal studies with detailed medication profiling.