Dravet Syndrome (DS) is a catastrophic developmental and epileptic encephalopathy (DEE) primarily caused by SCN1A haploinsufficiency. It is characterized by refractory hyperthermia-induced seizures, neurodevelopmental delay, and an elevated risk of sudden unexpected death in epilepsy (SUDEP) compared to other childhood epilepsies. While the small molecule fenfluramine (FFA) provides profound clinical benefit, its potential for systemic side effects and a poorly defined mechanism of action (MOA)...
Source: PubMed - functional seizures
·Published 30 Oct 2026 ·Imported 30 Oct 2026
Relevancy: Not reviewed
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