Seizures and epilepsy in MOG antibody-associated disease: from cortical neuroimmunology to clinical practice

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30 Oct 2026 0 comments

Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) is an inflammatory demyelinating disorder distinct from multiple sclerosis (MS) and aquaporin-4-IgG-positive neuromyelitis optica spectrum disorder (AQP4-NMOSD). Seizures are an important but incompletely characterized manifestation. Their reported prevalence is strongly age-dependent-approximately 30% in pediatric-onset versus 7% in adult-onset cohorts, although these estimates are influenced by referral and publication...