Case Report: A case of postneurosurgery Klebsiella pneumoniae meningitis with longitudinal CSF cytokine profiling and combined intrathecal therapy

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30 Oct 2026 0 comments

A 47-year-old woman with poorly controlled diabetes developed acute fever, headache, seizures, and progressive confusion during an admission for glycemic management. Neurological examination showed mild meningeal signs, and brain MRI demonstrated diffuse linear leptomeningeal enhancement. Lumbar puncture revealed strikingly viscous, 'jelly-like' cerebrospinal fluid (CSF), and culture identified Klebsiella pneumoniae. Despite systemic antimicrobial therapy, central inflammatory activity...