Case Report: Sporadic Creutzfeldt-Jakob disease initially misdiagnosed as ischemic stroke: a diagnostic challenge and biomarker-based clarification

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31 Oct 2026 0 comments

CONCLUSION: This case highlights the diagnostic challenge of early sCJD initially misdiagnosed as ischemic stroke in the presence of coexisting vascular pathology. Recognition of non-vascular diffusion patterns, careful reassessment of atypical clinical progression, and adjunctive CSF biomarker assessment may facilitate timely diagnostic reconsideration and help avoid unnecessary interventions.