Neurophysiological Mechanisms Underlying the Anticonvulsant Potential of Sarcococca saligna (D.Don) Mรผll.Arg. in Experimental Epilepsy

Author profile image Aggregator
0 comments
Sarcococca saligna (S. saligna), a medicinal plant, has traditionally been used due to its beneficial effects on the nervous system. This study evaluated the anticonvulsant efficacy of S. saligna methanolic extract (SSME) against pentylenetetrazol induced seizures (60 mg/kg) in Wistar rats. Sodium valproate (300 mg/kg, administered orally) served as the reference drug. Rats received SSME at doses of 250, 500, and 1000 mg/kg for seven days. The anticonvulsant potential of SSME was evaluated using...

Source: PubMed - functional seizures Published 03 Nov 2026 Imported 04 Nov 2026 Relevancy: Not reviewed

Read the article