POEMS syndrome mimicking diabetic peripheral neuropathy: a case report and literature review

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05 Nov 2026 0 comments

POEMS syndrome is a rare multisystem plasma cell disorder characterized by peripheral neuropathy and a broad spectrum of systemic manifestations. Because peripheral neuropathy may coexist with common metabolic disorders, POEMS syndrome can be easily overlooked or misdiagnosed. We report the case of a 64-year-old woman with a 2-year history of diabetes mellitus who presented with progressive numbness of all four limbs for more than 11 months and fatigue for approximately 1 year. She was initially...