Center-dependent "non-operability" in diffuse glioma: challenging assumptions through awake resection

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12 Nov 2026 0 comments

CONCLUSION: In selected patients referred for a second opinion, a prior "non-operable" designation did not preclude safe awake resection, suggesting that non-operability may partly reflect a center-related judgment. Patients initially deemed "non-operable" can achieve outcomes comparable to those of conventionally considered operable patients when managed in specialized high-volume centers with expertise in awake function-based craniotomy. These findings support systematic consideration of...