Paraneoplastic Neurological Syndrome Associated with Probable Small Cell Lung Cancer Initially Misdiagnosed as Disuse Syndrome and Delirium: A Case Report

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12 Nov 2026 0 comments

Paraneoplastic neurological syndrome (PNS) is an immune-mediated disorder in which neurological symptoms often precede tumor detection. We report the case of a 78-year-old woman with a history of heavy smoking and prior malignancy who presented with progressive cognitive impairment, athetosis, and conjugate eye deviation. She had been managed for disuse syndrome and delirium for six months before chest computed tomography (CT) revealed a right hilar mass. Paraneoplastic antibody testing revealed...