Imaging Features and Prognosis of Anti‑Sez6l2 Encephalitis: A Longitudinal Cohort Study and Literature Review

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27 Oct 2026 0 comments

Anti-Seizure-Related 6 Homolog Like 2 (Sez6l2) encephalitis is a rare autoimmune disorder characterized by cerebellar ataxia and cognitive impairment. The 13 previously reported cases included in our systematic analysis focus on adults, leaving gaps in pediatric demographics, longitudinal multimodal imaging markers, and effective management of refractory cases. This study aimed to expand the clinical spectrum, evaluate multimodal imaging in localizing neuroinflammation/monitoring response, and...