Beyond Seizure Suppression: Caffeic Acid Phenethyl Ester and 10-Hydroxy-2-Decenoic Acid Improve Anxiety-like and Cognitive Behaviors in PTZ-Challenged Zebrafish

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Epilepsy is associated with recurrent seizures and behavioral and cognitive disturbances, highlighting the importance of assessing behavioral outcomes alongside seizure severity. Caffeic acid phenethyl ester (CAPE) has shown neuroprotective activity, whereas evidence for the neurobehavioral effects of 10-hydroxy-2-decenoic acid (10-HDA) remains limited. This study investigated their individual and combined dietary effects on seizure-like behavior and behavioral test performance in adult...

Source: PubMed - functional seizures Published 27 Oct 2026 Imported 27 Oct 2026 Relevancy: Not reviewed

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