The Fluid Percussion Injury Model of Traumatic Brain Injury: Insights into Post-Traumatic Epilepsy and Comorbidities

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28 Oct 2026 0 comments

Traumatic brain injury (TBI) affects millions of people each year and can lead to persistent neurological disorders, including post-traumatic epilepsy (PTE). Animal models of concussion and TBI, developed since the late nineteenth century, provide a means to investigate injury progression and its consequences under controlled conditions. The lateral fluid percussion injury (LFPI) model is widely used to study both TBI and post-traumatic epileptogenesis. PTE is often resistant to antiseizure...