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FND

Trial By Error: When Primary Outcomes Yield Null Results in Clinical Trials, FND Experts Prefer Their Secondary Outcomes

Dr. David Tuller Added 18 Oct 2026 Relevancy: Not reviewed

By David Tuller, DrPH In 2020, the CODES study of cognitive behavior therapy (CBT) for psychogenic non-epileptic seizures, also known as dissociative seizures, reported null findings for its primary outcome—the number of seizures per month one year after the start of therapy. This was a disappointing result for an ambitious effort to seek an effective […]

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Trial By Error: A Letter Seeking a Correction in FMD Physiotherapy Paper

Dr. David Tuller Added 18 Oct 2026 Relevancy: Not reviewed

By David Tuller, DrPH I have recently written about a trial of an intervention for functional motor disorder (FMD) that had null results for its primary outcome—physical function as rated by the SF-36. The study–“Specialist Physiotherapy for functional motor disorder in England and Scotland (Physio4FMD): a pragmatic, multicentre, phase 3 randomised controlled trial,” published by […]

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Trial By Error: Edinburgh Study Links ME/CFS to “Blood-Based Biomarkers”

Dr. David Tuller Added 18 Oct 2026 Relevancy: Not reviewed

By David Tuller, DrPH Last year, a team from the University of Edinburgh released a pre-print called “Replicated blood-based biomarkers for myalgic encephalomyelitis not explicable by inactivity.” At the time, I posted an interview with the lead investigator, Chris Ponting, a professor of genetics at the university. The peer-reviewed version of the study has just […]

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Trial By Error: Updated Medical Textbook Still Promotes Biopsychosocial Ideology

Dr. David Tuller Added 18 Oct 2026 Relevancy: Not reviewed

By David Tuller, DrPH For decades, Kumar & Clark’s Clinical Medicine has been a standard textbook for medical education around the world. Last month, Elsevier pubished the 11th edition. The miniscule section on what it calls “chronic fatigue syndrome/myalgic encephalopathy” is pathetic. This section is in a chapter called “General Hospital Psychiatry,” promotes “psychological symptoms” […]

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Trial By Error: Study Finds Signs of “Functional Limb Weakness” in Patients Not Reporting Actual Limb Weakness

Dr. David Tuller Added 18 Oct 2026 Relevancy: Not reviewed

By David Tuller, DrPH *NOTE: Kim, an FND patient and advocate, has left an extensive set of criticisms in the comments. I urge those interested in this debate to read them. A recently published study about functional neurological disorder (FND) has reported some perplexing data. Of almost 300 patients diagnosed with Long Covid, 100 were […]

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Trial By Error: BMJ’s “Commissioned” Propaganda Piece Hijacked Death of Maeve Boothby O’Neill; Boothby O’Neill’s Mum Responds

Dr. David Tuller Added 18 Oct 2026 Relevancy: Not reviewed

By David Tuller, DrPH NOTE: Dr Zachary Grin, a physical therapist in New York City who specializes in functional neurological disorder (FND), left an interesting comment. I am re-posting it up here, with my response: Dr Grin: “David has misinterpreted the authors. They said “…functional impairment may lead to…”. Functional impairment refers to the limitation/loss […]

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Trial By Error: How Many Awful Papers Can Trudie Chalder Produce?

Dr. David Tuller Added 18 Oct 2026 Relevancy: Not reviewed

By David Tuller, DrPH *This is a crowdfunding month at UC Berkeley. If you’d like to support my work, the link is here. How many bad papers can Trudie Chalder, King’s College London’s factually and mathematically challenged professor of cognitive behavior therapy (CBT), churn out? The woman’s name seems attached to an inexhaustible supply of scientific […]

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Trial By Error: My Request for Correction of Causal Claim for Functional Neurological Symptoms

Dr. David Tuller Added 18 Oct 2026 Relevancy: Not reviewed

By David Tuller, DrPH This morning I sent the following letter to CNS Spectrums, a neuroscience journal published by Cambridge University Press. Subject line: “Correction needed for etiological statement in ‘Functional neurological symptoms occur commonly in healthy adults: implications for the pathophysiology of FND.'” Depending on the response, or lack of one, I might also […]

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Trial By Error: My Exchange with an FND Physical Therapy Specialist

Dr. David Tuller Added 18 Oct 2026 Relevancy: Not reviewed

By David Tuller, DrPH When I write about functional neurological disorder (FND) or functional neurological symptoms, I sometimes get feedback from Zachary Grin, a physical therapist in New York. As an FND specialist, he disagrees with pretty much everything I write about the topic. At first, I tried to engage with Zachary in a good-natured […]

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