Evaluating Age-Related Motor System Changes Using Gait as a Functionally Relevant Marker

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11 Nov 2026 0 comments

BACKGROUND AND OBJECTIVES: Aging causes gait and mobility decline, which often precedes cognitive impairment and dementia. Biological "age gaps" (the difference between biological and chronological age) are traditionally measured using neuroimaging and electroencephalography, quantified gait metrics have not been used for this purpose. We hypothesize that specific gait metrics can effectively quantify biological aging and predict future cognitive impairment risk.