Endothelial cell-specific TGM2 deficiency promotes progression of temporal lobe epilepsy by disrupting S1P metabolism and intercellular communication

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CONCLUSIONS: This study establishes a link between TGM2 and BBB function, metabolic pathways, and intercellular communication in TLE, providing an experimental basis for developing TLE therapeutic strategies targeting this pathway.

Source: PubMed - functional neurological disorder Published 23 Oct 2026 Imported 24 Oct 2026 Relevancy: Not reviewed

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