Double-blind, placebo-controlled randomised clinical trial on flexible doses of escitalopram and naltrexone in the treatment of men with compulsive sexual behaviour disorder: study protocol presentation

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28 Oct 2026 0 comments

BACKGROUND: Recent research has led to a better understanding of biological and psychosocial correlates of compulsive sexual behaviour disorder (CSBD). Psychotherapy is considered a first-line treatment strategy, while evidence on the use of pharmacotherapy is still scarce. This study aimed to provide new data on the efficacy of a selective serotonin reuptake inhibitor and an opioid receptor antagonist used as monotherapy or in combination in CSBD.