Organic Clues
A tag exploring clinical findings, objective abnormalities, and alternative disease processes that may point toward biological causes or warrant further investigation in cases labelled as FND.
When Stress-Sensitive Stiffness Was Diagnosed as Conversion Disorder
FND Nope
Moderator
A 52-year-old woman developed progressive leg stiffness, spasms and severe gait impairment that worsened with stress and fatigue. After multiple evaluations, she was diagnosed with conversion disorder. A year later, markedly elevated anti-GAD antibodies and characteristic EMG abnormalities supported stiff-person syndrome, with significant improvement following IVIG.
Diagnosed With FND After Three Weeks: 200 Seizures Later, Doctors Found Severe Hypoglycaemia
FND Nope
Moderator
Diagnosed with FND after three weeks, an Australian teenager endured around 200 seizures before severe hypoglycaemia linked to a gastrointestinal motility disorder was identified.
When Something Doesn’t Add Up: The MRI That Finally Gave Me Another Lead
Facebook Stories
Social media
After years of worsening symptoms, repeated A&E visits and an FND diagnosis that never fully seemed to fit, a long-awaited MRI finally revealed cervical spine abnormalities that now require further investigation. This is a patient story about persistence, uncertainty and the importance of taking another look when something does not add up.
The Falsification Problem: FND Resolved After CSF Leak Repair
FND Nope
Moderator
A patient diagnosed with FND recovered completely after surgical repair of a CSF leak. Why did the diagnosis remain? This article explores what the case reveals about comorbidity, diagnostic reasoning, and the falsification problem in FND.
The Common Phenotypes Hypothesis
Christoff
Spousal caregiver
An exploration of FND, positive rule-in signs, comorbidity, predictive processing, diagnostic closure, and whether functional symptoms may reflect common phenotypes arising from multiple underlying conditions.
Hoping one day we each will recover
Anonymous Parent
Parental caregiver
An 18-year-old developed severe neurological symptoms after a concussion, was diagnosed with FND after inconclusive testing, and later found to have tethered cord syndrome requiring surgery.
Fatigable Weakness vs Functional Weakness: Why Hoover’s Sign Can Mislead When Isokinetic Testing Shows Otherwise
Christoff
Spousal caregiver
Examines Hoover's sign in a patient with true fatigable weakness. Highlights how objective isokinetic testing better captures performance deficits than traditional clinical signs, preventing misinterpretation as functional weakness.
Current working hypothesis: Dynamic cord compression mistaken for FND
Christoff
Spousal caregiver
Over the years, along with various doctors, we have considered many hypotheses regarding my wife's medical condition, ranging from Parkinson's, Wilson's disease, Multiple Sclerosis (MS), hepatic encephalopathy, B12 deficiencies, CMT (Charcot-Marie-Tooth), and even, briefly, FND, until we realised how speculative such a diagnosis truly is (in essence, no diagnosis, MUS in sheep clothing)
Kairos moment: Gastrointestinal system
Christoff
Spousal caregiver
A short summary about my wife's gastroenterological journey that possibly led to her current neurological distress.
Kairos moment: Vestibular system
Christoff
Spousal caregiver
When observing my wife’s medical condition retrospectively, I try to identify what my late father used to call Kairos moments. In other words, identifying the tipping points, the moments in time that brought us to where we are now.
