Four Years of Dystonia: Meige Syndrome Misdiagnosed as FND
FND Nope
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A 2024 case report describes a 42-year-old woman diagnosed and treated for FND despite persistent facial, oral and cervical movements. After treatment failed, neurology diagnosed Meige syndrome. The authors explicitly describe the original FND diagnosis as a misdiagnosis.
When an Unexplained Gait Became Conversion Disorder: A Huntington’s Disease Case
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A 65-year-old woman with an abnormal gait, cognitive decline and psychiatric symptoms was diagnosed with conversion disorder after inconclusive neurological investigations. Years later, genetic testing confirmed Huntington’s disease—raising a difficult question: what positive evidence had established conversion disorder in the first place?
When Suppressible Movements Were Called Functional: A Genetic PKD Case
FND Nope
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A 14-year-old boy was diagnosed with a functional movement disorder after presenting with suppressible involuntary movements and psychiatric comorbidity. Further investigation identified monogenic paroxysmal kinesigenic dyskinesia (PKD), while the authors noted that specific positive features supporting the original functional diagnosis had been absent.
FND, Then Genetic Dystonia: A Pediatric DYT-TOR1A Case
FND Nope
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A pediatric patient diagnosed with Functional Neurological Disorder was later found to have DYT-TOR1A dystonia and responded well to deep brain stimulation. The authors retained FND as a coexisting diagnosis, raising an important question: once a genetic disorder capable of producing the movements was identified, what evidence determined which symptoms remained functional?
When Stress-Sensitive Stiffness Was Diagnosed as Conversion Disorder
FND Nope
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A 52-year-old woman developed progressive leg stiffness, spasms and severe gait impairment that worsened with stress and fatigue. After multiple evaluations, she was diagnosed with conversion disorder. A year later, markedly elevated anti-GAD antibodies and characteristic EMG abnormalities supported stiff-person syndrome, with significant improvement following IVIG.
When Conversion Disorder Was Actually a Rare Prion Disease
FND Nope
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A woman with tremor, speech problems and slowed movements was diagnosed with conversion disorder after early neurological investigations were unrevealing. As her condition progressively deteriorated, genetic testing ultimately confirmed Gerstmann–Sträussler–Scheinker disease caused by a rare PRNP mutation.
When “Functional” Signs Mislead: GSS Misdiagnosed as Conversion Disorder
FND Nope
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A man whose variable, distractible and inconsistent neurological findings contributed to a diagnosis of conversion disorder continued to deteriorate for years. After his death, neuropathology and genetic testing confirmed Gerstmann-Sträussler-Scheinker syndrome, showing how genuine clinical observations can support the wrong diagnostic interpretation.
A Case of Sporadic Creutzfeldt-Jakob Disease Presenting as Conversion Disorder
FND Nope
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A 64-year-old woman was diagnosed with a functional neurological movement disorder after clinicians observed distractibility, variability and entrainment. Within weeks, worsening symptoms and newly abnormal EEG and MRI findings reopened the investigation, and a brain biopsy confirmed sporadic Creutzfeldt-Jakob disease.
Written Off with FND: The Hidden Dental Abscess That Changed Everything
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After years of severe disability and an FND diagnosis, Sam’s family discovered a large, hidden abscess beneath a previously treated root-canal tooth. Within weeks of its removal and treatment, he began to regain his vision, mobility, clarity and independence. This is their story and a reminder that unexplained symptoms still deserve thorough investigation.
The Medical Journey of Megan Dixon: FND and Severe Disability
FND Nope
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Megan Dixon became severely disabled following childhood illness, with progressive loss of mobility and speech leading to prolonged hospitalisation. She was later reportedly diagnosed with FND and underwent extended rehabilitation after years of severe impairment.
